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Page 1
Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis.
Sveidahl Johansen O, Ma T, Hansen JB, Markussen LK, Schreiber R, Reverte-Salisa L, Dong H, Christensen DP, Sun W, Gnad T, Karavaeva I, Nielsen TS, Kooijman S, Cero C, Dmytriyeva O, Shen Y, Razzoli M, O'Brien SL, Kuipers EN, Nielsen CH, Orchard W, Willemsen N, Jespersen NZ, Lundh M, Sustarsic EG, Hallgren CM, Frost M, McGonigle S, Isidor MS, Broholm C, Pedersen O, Hansen JB, Grarup N, Hansen T, Kjær A, Granneman JG, Babu MM, Calebiro D, Nielsen S, Rydén M, Soccio R, Rensen PCN, Treebak JT, Schwartz TW, Emanuelli B, Bartolomucci A, Pfeifer A, Zechner R, Scheele C, Mandrup S, Gerhart-Hines Z. Sveidahl Johansen O, et al. Among authors: isidor ms. Cell. 2021 Jun 24;184(13):3502-3518.e33. doi: 10.1016/j.cell.2021.04.037. Epub 2021 May 27. Cell. 2021. PMID: 34048700 Free PMC article.
The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions.
Lund J, Breum AW, Gil C, Falk S, Sass F, Isidor MS, Dmytriyeva O, Ranea-Robles P, Mathiesen CV, Basse AL, Johansen OS, Fadahunsi N, Lund C, Nicolaisen TS, Klein AB, Ma T, Emanuelli B, Kleinert M, Sørensen CM, Gerhart-Hines Z, Clemmensen C. Lund J, et al. Among authors: isidor ms. Nat Metab. 2023 Apr;5(4):677-698. doi: 10.1038/s42255-023-00780-4. Epub 2023 Apr 13. Nat Metab. 2023. PMID: 37055619
MCT1 helps brown fat suck up succinate.
Lund J, Isidor MS, Gerhart-Hines Z. Lund J, et al. Among authors: isidor ms. Nat Metab. 2024 Mar;6(3):387-388. doi: 10.1038/s42255-024-00979-z. Nat Metab. 2024. PMID: 38378995 No abstract available.
White adipose remodeling during browning in mice involves YBX1 to drive thermogenic commitment.
Rabiee A, Plucińska K, Isidor MS, Brown EL, Tozzi M, Sidoli S, Petersen PSS, Agueda-Oyarzabal M, Torsetnes SB, Chehabi GN, Lundh M, Altıntaş A, Barrès R, Jensen ON, Gerhart-Hines Z, Emanuelli B. Rabiee A, et al. Among authors: isidor ms. Mol Metab. 2021 Feb;44:101137. doi: 10.1016/j.molmet.2020.101137. Epub 2020 Dec 5. Mol Metab. 2021. PMID: 33285300 Free PMC article.
Overexpression of cyclooxygenase-2 in adipocytes reduces fat accumulation in inguinal white adipose tissue and hepatic steatosis in high-fat fed mice.
Banhos Danneskiold-Samsøe N, Sonne SB, Larsen JM, Hansen AN, Fjære E, Isidor MS, Petersen S, Henningsen J, Severi I, Sartini L, Schober Y, Wolf J, Nockher WA, Wolfrum C, Cinti S, Sina C, Hansen JB, Madsen L, Brix S, Kristiansen K. Banhos Danneskiold-Samsøe N, et al. Among authors: isidor ms. Sci Rep. 2019 Jun 20;9(1):8979. doi: 10.1038/s41598-019-45062-w. Sci Rep. 2019. PMID: 31222118 Free PMC article.